New evidence pyramid

Interesante articulo;

Evid Based Med doi:10.1136/ebmed-2016

New evidence pyramid

Open Access

  1. M Hassan Murad,
  2. Noor Asi,
  3. Mouaz Alsawas,
  4. Fares Alahdab

“The first and earliest principle of evidence-based medicine indicated that a hierarchy of evidence exists. Not all evidence is the same. This principle became well known in the early 1990s as practising physicians learnt basic clinical epidemiology skills and started to appraise and apply evidence to their practice. Since evidence was described as a hierarchy, a compelling rationale for a pyramid was made. Evidence-based healthcare practitioners became familiar with this pyramid when reading the literature, applying evidence or teaching students……”


The Changing Face of Clinical Trials: Pragmatic Trials

Interesante publicación en el NEJM.

Pragmatic Trials

Ian Ford, Ph.D., and John Norrie, M.Sc.

N Engl J Med 2016; 375:454-463August 4, 2016DOI: 10.1056/NEJMra1510059

Pragmatism in clinical trials arose from concerns that many trials did not adequately inform practice because they were optimized to determine efficacy.1 Because such trials were performed with relatively small samples at sites with experienced investigators and highly selected participants, they could be overestimating benefits and underestimating harm. This led to the belief that more pragmatic trials, designed to show the real-world effectiveness of the intervention in broad patient groups, were required. Medical researchers, both academic and commercial, must deliver health care innovations (drugs, devices, or other interventions) that are safe, beneficial, and cost-effective, and they must identify the subgroups for whom the innovation will provide the greatest benefit relative to risk. A broad view of an intervention, including approaches to improve its effectiveness, is critical. An ideal trial includes a population that is relevant for the intervention, a control group treated with an acceptable standard of care, and outcomes that are meaningful, and it must be conducted and analyzed at a high standard of quality. Pragmatic trials frequently include complex interventions, sometimes consisting of several interacting components2 and often involving the skills and experience of one or more health care professionals to deliver the intervention — for example, surgeons, physiotherapists, or cognitive behavioral therapists.

In this article, we do not provide a definitive exposition of the methods used for pragmatic trials. Rather, we explore the contexts in which a pragmatic design is most and least attractive and identify the strengths and limitations of — and challenges in implementing — pragmatic trials.”


Evidence Based Medicine Reviews (EBMR)

muy buenos días, compañeros, os adjunto un vídeo formativo sobre EBM, gracias a OVID, por la elaboración.

Desde el Servicio de Bibliotecas de Ribera Salud, os deseamos buen verano.

Evidence Based Medicine Reviews (EBMR)

Es un recurso que combina en la plataforma Ovid 7 bases de datos de diferentes fuentes de Medicina Basada en la Evidencia (MBE) entre ellos las revisiones sistemáticas del Cochrane

Introducción a Cochrane en Ovid (EBMR) Video Formativo


La evidencia basada en la práctica clínica: Resumen de las amenazas a la validez de pruebas y cómo minimizarlos

Interesante articulo del 2016, publicado en la revista European Journal of Internal Medicine. 2016.

Evidence-based clinical practice: Overview of threats to the validity of ecidence and how to minimise them.


Disponible en nuestra biblioteca.

  • Review Article
  • European Journal of Internal Medicine, Volume 32, July 2016, Pages 13-21
  • Silvio Garattini, Janus C. Jakobsen, Jørn Wetterslev, Vittorio Bertelé, Rita Banzi, Ana Rath, Edmund A.M. Neugebauer, Martine Laville, Yvonne Masson, Virginie Hivert, Michaela Eikermann, Burc Aydin, Sandra Ngwabyt, Cecilia Martinho, Chiara Gerardi, Cezary A. Szmigielski, Jacques Demotes-Mainard, Christian Gluud

Cochrane EBM; informacion sobre uso

Sobre la base de datos Cochrane que en Ovid se llama Evidence Based Medicine Reviews os remito más abajo un enlace a un video de formación en inglés, además en el adjunto está la transcripción del video en inglés.


Herramienta MBE

Os adjunto un enlace de una herramienta para MBE, donde podeis encontar teoria y tambien ejemplos, espero que os guste.